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Year | Number of Results |
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Page 1
Remdesivir triphosphate blocks DNA synthesis and increases exonucleolysis by the replicative mitochondrial DNA polymerase, Pol γ.
Mitochondrion. 2021 Nov;61:147-158. doi: 10.1016/j.mito.2021.09.010. Epub 2021 Oct 5.
Mitochondrion. 2021.
PMID: 34619353
Free PMC article.
Analysis of Human Mitochondrial DNA Content by Southern Blotting and Nonradioactive Probe Hybridization.
Wheeler JH, Young CKJ, Young MJ.
Wheeler JH, et al. Among authors: young ckj.
Curr Protoc Toxicol. 2019 Jun;80(1):e75. doi: 10.1002/cptx.75. Epub 2019 Apr 14.
Curr Protoc Toxicol. 2019.
PMID: 30982231
Free PMC article.
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Heterozygous p.Y955C mutation in DNA polymerase γ leads to alterations in bioenergetics, complex I subunit expression, and mtDNA replication.
Rahman MM, Young CKJ, Goffart S, Pohjoismäki JLO, Young MJ.
Rahman MM, et al. Among authors: young ckj.
J Biol Chem. 2022 Aug;298(8):102196. doi: 10.1016/j.jbc.2022.102196. Epub 2022 Jun 24.
J Biol Chem. 2022.
PMID: 35760101
Free PMC article.
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The antiretroviral 2',3'-dideoxycytidine causes mitochondrial dysfunction in proliferating and differentiated HepaRG human cell cultures.
Young CKJ, Wheeler JH, Rahman MM, Young MJ.
Young CKJ, et al.
J Biol Chem. 2021 Jan-Jun;296:100206. doi: 10.1074/jbc.RA120.014885. Epub 2020 Dec 31.
J Biol Chem. 2021.
PMID: 33334881
Free PMC article.
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Identification of Somatic Mitochondrial DNA Mutations, Heteroplasmy, and Increased Levels of Catenanes in Tumor Specimens Obtained from Three Endometrial Cancer Patients.
Young MJ, Sachidanandam R, Hales DB, Brard L, Robinson K, Rahman MM, Khadka P, Groesch K, Young CKJ.
Young MJ, et al. Among authors: young ckj.
Life (Basel). 2022 Apr 9;12(4):562. doi: 10.3390/life12040562.
Life (Basel). 2022.
PMID: 35455053
Free PMC article.
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Analysis of Mitochondrial DNA Polymorphisms in the Human Cell Lines HepaRG and SJCRH30.
Young MJ, Jayaprakash AD, Young CKJ.
Young MJ, et al. Among authors: young ckj.
Int J Mol Sci. 2019 Jul 2;20(13):3245. doi: 10.3390/ijms20133245.
Int J Mol Sci. 2019.
PMID: 31269646
Free PMC article.
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Comparison of HepaRG cells following growth in proliferative and differentiated culture conditions reveals distinct bioenergetic profiles.
Young CKJ, Young MJ.
Young CKJ, et al.
Cell Cycle. 2019 Feb;18(4):476-499. doi: 10.1080/15384101.2019.1578133. Epub 2019 Feb 12.
Cell Cycle. 2019.
PMID: 30755072
Free PMC article.
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